外源性孕激素诱导的急性疹与体外受精相关
Shilpa Clara Joseph1, Jayashree S2, Ashwini P K3
1Department of Pharmacy Practice, JSS College of Pharmacy, Mysore, Karnataka, India.
BMJ case reports
|February 14, 2025
概括
急性疹是一种罕见的药物不良反应,在体外受精 (IVF) 期间外源性孕激素的使用后可能发生. 这个案例突出了诊断和成功的管理,使怀孕成为可能.
科学领域:
- 生殖医学 生殖医学
- 皮肤病学 皮肤病学
- 临床药理学 临床药理学
背景情况:
- 外源性孕激素对于胚胎植入和体外受精 (IVF) 妊娠成功至关重要.
- 对孕激素的过敏反应很少见,但可以表现为药物不良反应.
- 对于接受生育治疗的患者来说,急性疹是一种严重的担忧.
研究的目的:
- 在接受试管婴儿治疗的患者中报告一种罕见的外源性孕激素引起的急性疹病例.
- 描述诊断过程,包括去挑战和重新挑战,用于孕激素诱导的过敏症.
- 强调在辅助生殖技术中识别和管理药物不良反应的重要性.
主要方法:
- 一个30多岁的女性,患有初级不孕症,接受试管婴儿的案例研究.
- 临床表现是普遍的疹和疹.
- 通过药物去挑战和重新挑战来确认诊断,排除其他原因.
主要成果:
- 患者在她的试管婴儿周期中患有急性疹,这归因于外源性孕激素的使用.
- 症状治疗导致过敏反应的解决.
- 患者在同一个治疗周期中成功怀孕,并分娩了一个健康的婴儿.
结论:
- 外源性孕激素诱导的急性疹是一种罕见但可控的不良药物反应.
- 及时诊断和症状治疗对于患者的福祉和治疗的延续至关重要.
- 即使在体外受精中对孕激素发生过敏反应后,也可以获得成功的妊娠结果.
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