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用于有效检测细菌病原体的Aptamer-modified MOFs (Aptamer@MOF):一个审查

Shilan Arif Fatah¹, Khalid M Omer¹

¹Department of Chemistry, College of Science, University of Sulaimani, Qliasan Street, 46002 Sulaymaniyah, Kurdistan Region, Iraq.

ACS applied materials & interfaces

|February 14, 2025

概括

金属有机框架 (MOF) 与体结合,可以创建用于检测致病细菌的先进生物传感器. 这种协同作用提高了公共卫生和安全应用的检测灵敏度和选择性.

科学领域:

纳米技术和材料科学材料科学
生物技术和生物传感技术
分析化学分析化学

背景情况:

检测致病细菌对于公共卫生,食品和水安全至关重要.
现有的检测方法往往在灵敏度,选择性或速度方面面临限制.
金属有机框架 (MOF) 为生物传感器开发提供可调节的特性和稳定性.

研究的目的:

审查APTAMER和MOF的整合,以提高细菌检测.
为了突出aptamer@MOF生物传感器的协同优势.
讨论当前的挑战和该领域的未来方向.

主要方法:

关于APTAMER功能化的MOF (aptamer@MOF) 生物传感器的文献综述.
在MOF平台上讨论各种aptamer固定化策略.
分析这些生物传感器使用的不同检测技术.

主要成果:

Aptamer@MOF生物传感器在细菌检测方面表现出提高的灵敏度,选择性和多功能性.
这些生物传感器可以实时和定量分析致病细菌.
在食品安全,环境监测和诊断方面注意到成功的应用.

结论:

Aptamer@MOF生物传感器代表了用于细菌检测的高性能平台.
需要进一步的研究来应对敏感性,选择性,稳定性和可扩展性的挑战.
优化和扩展应用将推动这些先进生物传感器的现实实用性.

关键词:

一个适应者@MOFF 亚博体育官网亚博体育官网亚博体育官网亚博体育官网亚博体育官网细菌检测检测细菌检测检测细菌检测生物传感器是一种生物传感器.金属-有机框架的框架.

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