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Updated: May 28, 2025

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一个重组DNA聚合酶的半理性演变,用于改造核酸的纳入效率

Lili Zhai1,2, Zi Wang1, Fen Liu3

  • 1BGI Research, Shenzhen, China.

PloS one
|February 14, 2025
PubMed
概括

研究人员设计了一种DNA聚合酶 (KOD pol),以改进3'-O-修饰核酸的结合. 一种变体Mut_E10显示出超过20倍的增强活性和DNA测序应用的潜力.

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