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相关概念视频

In-vitro Mutagenesis01:16

In-vitro Mutagenesis

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To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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Replication in Eukaryotes02:31

Replication in Eukaryotes

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Replication in Prokaryotes02:35

Replication in Prokaryotes

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The Scientific Method01:32

The Scientific Method

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The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
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Recombinant DNA01:09

Recombinant DNA

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Reproductive Cloning01:27

Reproductive Cloning

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Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic...
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相关实验视频

Updated: May 28, 2025

Shotgun Proteomics Sample Processing Automated by an Open-Source Lab Robot
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GitHub使协作和可重复的实验室研究成为可能.

Katharine Y Chen1, Maria Toro-Moreno1, Arvind Rasi Subramaniam1

  • 1Basic Sciences Division and Computational Biology Section of the Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.

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|February 14, 2025
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概括

GitHub通过提供追踪所有项目活动的框架来增强实验室研究文档. 本指南解释了如何将GitHub集成到湿实验室工作流程中,以改善数据管理.

科学领域:

  • 计算生物学 计算生物学
  • 生物信息学是一种生物信息学.
  • 实验室科学 实验室科学

背景情况:

  • 传统的实验室文档方法可能是分散的,缺乏版本控制.
  • 科学研究中的可复制性是一个日益关注的问题.
  • 数字工具在科学研究中越来越多地被采用.

研究的目的:

  • 为突出使用GitHub用于实验室研究文档的优点.
  • 提供关于将GitHub集成到"湿"实验室工作流程中的实际指导.
  • 促进科学数据管理和合作的最佳实践.

主要方法:

  • 使用GitHub的版本控制功能来处理实验数据和协议.
  • 实施GitHub用于项目管理,问题跟踪和协作写作.
  • 利用GitHub页面来提供可访问的项目文档和数据共享.

主要成果:

  • 提高实验结果的可追溯性和可复制性.
  • 加强研究小组成员之间的协作.
  • 所有与研究相关的文物的集中和版本控制的存储库.

结论:

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  • GitHub提供了一个强大而通用的平台,用于现代化"湿"实验室文档.
  • 集成GitHub可以显著提高研究效率,透明度和数据完整性.
  • 采用GitHub促进了一个更具协作性和可重复性的研究环境.