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Updated: May 28, 2025

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
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A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

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艾滋病毒-1适应了由CD4+和CD8+ T细胞施加的与HLAII类相关的选择压力

Eric Alves1, Jennifer Currenti1, Keeley Crawford1

  • 1School of Human Sciences, University of Western Australia, Crawley, Western Australia, Australia.

Science advances
|February 14, 2025
PubMed
概括

从人类白细胞抗原II类 (HLA-II) 受限制的T细胞中脱离HIV-1突变的突变对疫苗开发构成了挑战. 这项研究揭示了各种病毒适应机制及其与疾病进展的联系.

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