蛋白质丰富的口服营养补充剂对中年和老年女性肌肉功能的有效性:一项随机对照试验
Minji Kang1, Hyunkyung Rho2, Minhui Kim1
1Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Giheong-gu, Yongin 17104, Republic of Korea; Research Institute of Medical Nutrition, Kyung Hee University, Dongdaemoon-gu, Seoul 02447, Republic of Korea.
富含蛋白质的口服营养补充剂 (ONS) 有助于维持瘦体质 (LBM) 并防止12周内在老年女性中增加脂肪质量 (FM). 这种干预措施有望预防虚弱和与年龄有关的肌肉骨问题.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 人体生理学 人体生理学
背景情况:
- 女性的老龄化与缩症和脂肪量增加有关,有助于肌肉骨疾病和肌肉骨疾病.
- 维持足够的蛋白质摄入量对于保持老年人肌肉质量和功能至关重要.
研究的目的:
- 评估12周蛋白质丰富口服营养补充剂 (ONS) 对中年和老年女性肌肉质量,力量和功能的影响.
- 评估瘦肉体质量 (LBM),体脂质量 (FM),肌肉力量和体力表现的变化.
主要方法:
- 一个为期12周的单中心,双盲,随机对照试验,涉及70名50-80岁的健康女性.
- 参与者每天服用两包蛋白质丰富的ONS (15g蛋白质) 或安慰剂ONS.
- 主要结局是LBM;次要结局包括肌肉强度,体力表现,炎症标志物和FM.
主要成果:
- 与安慰剂组相比,与蛋白质丰富的ONS组显示出LBM在统计学上显著的更高的百分比变化 (p=0.020).
- 而安慰剂组体验到身体脂肪量显著增加 (p<0.01).
- 两组之间没有观察到肌肉力量,体力表现或炎症标志物的显著差异.
结论:
- 富含蛋白质的ONS消费有效地帮助维持LBM,并防止中年和老年妇女的脂肪质量增加.
- 这种补充策略可能有助于预防女性的脆弱性和与年龄相关的肌肉骨疾病.
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