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Updated: May 28, 2025

Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis
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准高流动性组蛋白B2通过调节miR-21对低毒性肺高血压产生抗增殖作用

Pan Wang1, Xu Zhang2, Mengge Yao2

  • 1The Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and pathophysiology, The School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China; Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, China; Key Laboratory of Cardio-Thoracic Surgery, Fujian Medical University, Fujian Province University, Fuzhou, China; Department of Clinical Laboratory, Xi'an Fifth Hospital, Xi'an, China.

Toxicology and applied pharmacology
|February 14, 2025
PubMed
概括

高流动性组盒子2 (HMGB2) 通过增加血管细胞增殖,驱动肺高血压 (PH). 准cGMP/PKG-SOX2-miR-21-TPM1通路为PH提供了潜在的治疗策略.

关键词:
在HMGB2中,它是HMGB2.低毒性肺高血压是什么这就是TMP1的特点.cGMP/PKG信号通路的使用这就是为什么miR-21

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