在非紧急输血中扩大液体血的使用:一个单一的学术机构的经验
Joseph P Connor1, Soumya Jaladi1, Wenjing Cao2
1Section of Transfusion Medicine, Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, USA.
Transfusion
|February 14, 2025
概括
液体血 (LP),立即输血而不冷,可以安全地用于手术和例行输血,防止浪费,并没有显示与解血相比负面的临床结果.
科学领域:
- 输血医学 输血医学
- 血液学 血液学 血液学
- 手术护理 手术护理
背景情况:
- 液体血 (LP) 是一种不冷输血的血液产品,主要用于大规模输血.
- 将LP的使用扩展到手术和例行输血的目的是尽量减少产品的浪费.
研究的目的:
- 评估在手术和例行输血中使用液体血 (LP) 的临床结果.
- 在非大规模输血场景中,比较LP与解血 (TP) 的疗效和安全性.
主要方法:
- 对890个涉及LP输血的病例进行了回顾性图表审查.
- 按指示 (紧急,手术,常规) 和输血的部分 (≤50%或>50%) 分类LP使用.
- 将LP病例与仅接受TP常规输血的对照组进行比较.
主要成果:
- 在34%的紧急,44%的手术和11%的例行输血中使用LP.
- 在较高的LP分数或在比较LP与TP时,没有观察到凝血病的纠正,需要额外的血液制品或死亡率的显著差异.
- 结果在常规输血中与较高LP分数以及LP和TP输血事件之间一致.
结论:
- 在手术和常规输血中使用LP是安全的,不会恶化临床结果.
- 在患者护理中支持LP的更广泛应用,可能减少产品浪费.
- 建议对LP利用进行进一步的研究.
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