确保通过电子表格输入与实验相关的元数据遵守标准.
Martin J O'Connor1, Josef Hardi2, Marcos Martínez-Romero2
1Stanford Center for Biomedical Informatics Research, Stanford, CA, 94305, USA. martin.oconnor@stanford.edu.
Scientific data
|February 14, 2025
概括
研究人员现在可以使用电子表格输入元数据,同时确保数据标准的合规性. 这种方法提高了实验结果的数据质量和一致性,特别是在生物医学研究中.
科学领域:
- 生物医学研究的研究.
- 数据科学是数据科学.
- 科学信息学科学信息学
背景情况:
- 科学家需要高质量的元数据来获得实验结果.
- 电子表格通常用于元数据输入,但缺乏一致性和正式合规性.
- 研究人员对现有的数据注释工具的使用不足.
研究的目的:
- 使用电子表格进行元数据输入的端到端方法.
- 确保遵守基于社区的元数据标准,并提供质量控制.
- 支持HuBMAP生物医学联盟收集测试元数据.
主要方法:
- 使用可定制模板,代表元数据标准.
- 集成对元数据值的受控术语和本体学.
- 采用互动式基于Web的工具来识别和纠正错误.
主要成果:
- 开发的方法促进了基于电子表格的元数据输入.
- 它确保严格遵守元数据标准,并提高数据质量.
- 该系统在HuBMAP联盟中成功部署.
结论:
- 这种方法弥合了熟悉的电子表格使用和严格的元数据标准之间的差距.
- 它提高了生物测试元数据的质量和一致性.
- 该方法为大规模研究计划中的数据注释提供了实用解决方案.
相关概念视频
Microsoft Excel: Plotting Mean, SD, and SE
143
In Microsoft Excel, plotting the mean along with standard deviation (SD) and standard error (SE) helps visualize data variability and reliability. To plot these values, follow these steps:
First, calculate the mean, SD, and SE of your data. The mean is obtained using the formula `=AVERAGE(range)`, while SD can be calculated with `=STDEV.P(range)` for a population or `=STDEV.S(range)` for a sample. SE is calculated as `=SD/SQRT(n)`, where `n` is the sample size.
To plot these values, use a bar...
First, calculate the mean, SD, and SE of your data. The mean is obtained using the formula `=AVERAGE(range)`, while SD can be calculated with `=STDEV.P(range)` for a population or `=STDEV.S(range)` for a sample. SE is calculated as `=SD/SQRT(n)`, where `n` is the sample size.
To plot these values, use a bar...
143
Data Validation
141
Method validation is a crucial process in analytical chemistry designed to confirm that a given method consistently produces reliable and high-quality results. This process is essential when a method is applied to different sample matrices or when procedural modifications are made, ensuring that the results meet acceptable standards across various applications.
Key parameters for method validation include:
Key parameters for method validation include:
141
Ethics in Research
22.9K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
22.9K
Data Collection by Experiments
23.7K
Data collection is a systematic method of obtaining, observing, measuring, and analyzing accurate information. An experimental study is a standard method of data collection that involves the manipulation of the samples by applying some form of treatment prior to data collection. It refers to manipulating one variable to determine its changes on another variable. The sample subjected to treatment is known as “experimental units.”
An example of the experimental method is a public...
An example of the experimental method is a public...
23.7K
The Scientific Method
223.6K
The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
223.6K


