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相关概念视频

Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

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The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
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Atomic Nuclei: Nuclear Relaxation Processes01:23

Atomic Nuclei: Nuclear Relaxation Processes

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In the absence of an external magnetic field, nuclear spin states are degenerate and randomly oriented. When a magnetic field is applied, the spins begin to precess and orient themselves along (lower energy) or against (higher energy) the direction of the field. At equilibrium, a slight excess population of spins exists in the lower energy state. Because the direction of the magnetic field is fixed as the z-axis,  the precessing magnetic moments are randomly oriented around the z-axis.
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NMR Spectroscopy: Spin–Spin Coupling01:08

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The spin state of an NMR-active nucleus can have a slight effect on its immediate electronic environment. This effect propagates through the intervening bonds and affects the electronic environments of NMR-active nuclei up to three bonds away; occasionally, even farther. This phenomenon is called spin–spin coupling or J-coupling. Coupling interactions are mutual and result in small changes in the absorption frequencies of both nuclei involved. While nuclei of the same element are involved...
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Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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The magnetic field due to a volume current distribution given by the Biot–Savart Law can be expressed as follows:
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Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
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使用受约束的球形解卷在多扩散权重磁共振成像中的结构连接体构造.

Marlene Tahedl1, J-Donald Tournier2,3, Robert E Smith4,5

  • 1Department of Neuroradiology, School of Medicine and Health, Technical University of Munich, Munich, Germany. marlene.tahedl@tum.de.

Nature protocols
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概括
此摘要是机器生成的。

本研究详细介绍了一种使用先进的扩散权重磁共振成像 (dMRI) 技术和软件工具生成高质量的结构连接组 (SC) 脑连接图的协议.

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科学领域:

  • 神经成像是一种神经成像.
  • 计算神经科学是一种神经科学.
  • 神经解剖学是一个神经解剖学.

背景情况:

  • 结构连接组 (SC) 地图表是从体内扩散权重磁共振成像 (dMRI) 数据生成的.
  • 基于网络的分析方法被采用为大脑连接研究.

研究的目的:

  • 为生成高质量的脑连接SCs提供一个逐步的协议.
  • 利用最近在dMRI数据处理和曲谱学方面的进展来提高生物准确性.

主要方法:

  • 使用具有受约束球形解卷的多层dMRI数据,以提高纤维方向估计和组织信号的分离.
  • 实施解剖学上受约束的轨迹学和球形解卷信息过的轨迹图,以提高轨迹学准确性.
  • 使用MRtrix3软件实现协议,使用FSL软件执行特定的处理任务.

主要成果:

  • 该协议可以生成高质量的SCs,对交叉纤维的敏感性增加,生物精度提高.
  • 中间步骤可以适应相关分析,例如基于兴趣的区域曲谱学和局部白质物质性质量化.

结论:

  • 本协议提供了一种标准化方法,用于创建精确的结构连接组图.
  • 该程序适合具有dMRI和神经科学专业知识的用户,需要213小时的计算时间.