感知HBV相关的耻辱感与慢性乙型肝炎B患者的抗病毒药物坚持程度较低有关
Hee-Soon Juon1, Daniel Yang1, Cindy Xin Fang1
1Department of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Journal of viral hepatitis
|February 15, 2025
概括
患有慢性乙型肝炎 (CHB) 的韩国裔美国人的药物坚持受年龄,对CHB的了解和感知的耻辱影响. 提高坚持要求解决个人和医疗保健因素,以更好地管理肝病.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
- 行为科学 行为科学
背景情况:
- 慢性乙型肝炎 (CHB) 患者的药物不服可以加速肝病进展为肝硬化和肝细胞癌 (HCC).
- 了解高风险族群 (如朝鲜裔美国人) 的坚持因素对于有效管理至关重要.
研究的目的:
- 调查影响韩国裔美国人CHB患者药物坚持的心理社会和临床因素.
- 在这个人群中确定特定的抗病毒疗法坚持的决定因素.
主要方法:
- 调查了来自费城和洛杉矶的365名韩裔美国人CHB患者.
- 8项莫里斯基药物坚持度表 (MMAS-8) 评估了对抗病毒药物的坚持.
- 描述性和多变量逻辑回归分析确定了与MMAS-8分数相关的因素.
主要成果:
- 78%的参与者接受了抗病毒治疗,69%的参与者表现出中等到高的坚持.
- 年龄较大,对CHB后续的更多知识,较低的HBV污名感知和药房计划与更高的药物坚持有关.
- 年龄较小,知识较少,耻辱感较高,缺乏药房计划与较低的遵守率有关.
结论:
- 个人因素,如对CHB的了解和感知到的耻辱感,以及医疗保健因素,如药房计划,显著影响药物坚持.
- 建议针对这些个人因素进行有针对性的教育干预,以改善韩裔美国人CHB患者的坚持.
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