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Updated: May 27, 2025

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

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通过与MMPs和JAK1/2的相互作用来调节骨髓瘤细胞的转移潜力7-Geranyloxycoumarin

Fatemehsadat Hosseini1, Abdolreza Ahmadi1, Zahra Nasiri Sarvi1

  • 1Novel Diagnostics and Therapeutics Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran.

Naunyn-Schmiedeberg's archives of pharmacology
|February 15, 2025
PubMed
概括

一种天然化合物7-Geranyloxycoumarin通过准Janus激酶 (JAKs) 和矩阵金属蛋白酶 (MMPs) 来有效地抑制骨髓瘤瘤 (OS) 细胞的转移. 这项研究突出了其作为骨癌新型治疗剂的潜力.

关键词:
7 - 杰拉尼洛克西库马林在JAK/STAT路径中.抑制MMP的抑制作用转移 转移 转移 转移骨质肉瘤骨质肉瘤是什么

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Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models04:25

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