2型糖尿病老年人的长期虚弱和身体表现转变. 在MIDFRAIL随机临床研究中
Olga Laosa1, Eva Topinkova2, Isabelle Bourdel-Marchasson3
1Foundation for Biomedical Research-University Hospital of Getafe, Madrid, Spain; Biomedical Research Center Network for Frailty and Healthy Ageing (CIBERFES), Institute of Health Carlos III, Madrid, Spain.
The journal of nutrition, health & aging
|February 15, 2025
概括
这项研究发现,一项为期16周的干预措施改善了2型糖尿病 (T2D) 的老年人虚弱和身体功能. 与通常护理相比,MIDFRAIL干预导致了更好的结果.
科学领域:
- 老年学是一门学科.
- 内分泌学 在内分泌学.
- 物理疗法物理治疗
背景情况:
- 2型糖尿病 (T2D) 与老年人的脆弱性有关.
- 脆弱性会对老龄人口的健康状况和生活质量产生负面影响.
研究的目的:
- 评估MIDFRAIL干预对T2D老年人脆弱状态的长期影响.
- 评估干预后身体功能的变化.
主要方法:
- 一个集群随机试验,涉及298名社区老年人 (>70岁) 患有T2D.
- 干预组接受了抵抗运动,营养教育和16周的优化糖尿病护理.
- 在基线和18-24个月时使用 Fried Frailty Phenotype 评估脆弱性和使用 SPPB 评估身体功能.
主要成果:
- 与常规护理组 (UCG) 相比,干预组 (IG) 的脆弱性状况改善和脆弱性标准降低的可能性更高.
- IG参与者更有可能提高他们的SPPB得分,这表明身体功能得到改善.
- 特别是在未成年参与者中特别注意到好处.
结论:
- 在长期随访期间,MIDFRAIL干预有效地改善了T2D老年人的脆弱状态和身体功能.
- 这种全面的干预提供了一种有希望的方法来对抗这一群体的脆弱性.
相关概念视频
Carbohydrate Metabolism
10.7K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
10.7K
Diabetes: Symptoms, Diagnosis, and Complications
498
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
498
Cognitive Development During Adulthood
45
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
45


