基于HAPA理论的病例管理对与代谢功能障碍相关的脂肪性肝病患者的影响
Jia Mei1, Yuncai Xie1, Pingping Huang1
1Health Medicine Center, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China.
Annals of hepatology
|February 15, 2025
概括
基于健康行动过程方法 (HAPA) 的管理显著改善了与代谢功能障碍相关的脂肪性肝病 (MASLD) 患者的结果. 这种干预措施在六个月内增强了肝功能,脂质概况和健康行为.
科学领域:
- 肝病学和代谢疾病
- 健康心理学和行为科学健康心理学和行为科学
- 预防医学和公共卫生
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 是一个普遍且日益严重的全球健康问题.
- 有效的管理策略对于缓解MASLD的进展和并发症至关重要.
- 健康行动过程方法 (HAPA) 为理解和促进健康行为提供了一个理论框架.
研究的目的:
- 评估基于健康行动过程方法 (HAPA) 的健康管理在MASLD患者中的有效性.
- 评估基于HAPA的干预对MASLD患者临床标志物,生化指数和健康行为的影响.
主要方法:
- 这是一项随机对照试验,涉及204名MASLD患者.
- 实验组接受了基于HAPA理论的病例管理;对照组接受了标准护理.
- 在6个月内评估了干预效应,测量了BMI,WHR,肝功能 (AST,ALT),血脂和健康行为 (HPLP-II).
主要成果:
- 基于HAPA的干预组显示脂肪肝状况显著改善 (P < 0.01).
- 在实验组中观察到BMI,WHR和关键生化指数的显著降低 (P <0.05).
- 改善的HDL-C水平 (P < 0.001) 和优越的健康行为评分 (压力管理,运动,饮食,健康责任) 在HAPA组 (P < 0.01) 中被注意到.
结论:
- 基于HAPA理论的病例管理是改善MASLD患者临床和行为结果的有效策略.
- 这种方法对脂质特征,肝功能和与健康相关的行为产生积极影响,为MASLD管理提供了一个有前途的途径.
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