乐团德尔菲共识:在固体器官移植接受者中,SARS-CoV-2感染的诊断和治疗管理
Beatrice Tazza1, Natascia Caroccia1, Alice Toschi2
1Infectious Diseases Unit, Department for Integrated Infectious Risk Management, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
概括
这项研究为在实体器官移植 (SOT) 接受者中管理SARS-CoV-2感染提供了专家共识的指导,解决了关键的知识差距. 这些发现旨在规范护理并改善这个脆弱的患者群体的治疗结果.
科学领域:
- 传染性疾病 传染性疾病
- 移植医学 移植医学 移植医学
- 病毒学 病毒学
背景情况:
- 固体器官移植 (SOT) 接受者是一个脆弱的人群,在管理SARS-CoV-2感染方面面临独特的挑战.
- 现有的针对这一群体的具体证据有限,需要专家指导.
研究的目的:
- 解决SOT受体中SARS-CoV-2风险分层,诊断,治疗和一般管理方面的知识差距.
- 为临床医生提供专家共识,基于证据的指导.
主要方法:
- 由传染病和临床药理学专家进行了全面的范围文献审查.
- 开发了一份28项调查问卷,并使用双轮Delphi方法向21名专家组成的小组进行管理.
主要成果:
- 在经过两轮专家审查后,就10个关键声明达成共识.
- 专家小组由来自不同国际地点的21名专家组成.
结论:
- 由此产生的共识陈述提供了一个标准化为感染SARS-CoV-2的SOT接收者提供护理的框架.
- 本指南旨在改善高风险人群中缺乏强有力的证据的临床实践和结果.
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