美国成年人中饮食中素摄入量与结石之间的关联
Jian Wu1,2
1Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China. wuxiaojianxy@163.com.
Scientific reports
|February 15, 2025
概括
饮食中较高的酸摄入量与美国成年人结石风险降低有关. 这种保护性关联在60岁以下的个体中尤为明显,这表明氨酸.
科学领域:
- 营养流行病学 营养流行病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 关于饮食中氨酸与结石形成之间的联系的证据有限.
- 结石是一个重要的健康问题,影响了相当一部分成年人群.
- 了解影响结石风险的饮食因素对于预防策略至关重要.
研究的目的:
- 调查饮食中素摄入量与美国成年人结石患病率之间的关联.
- 探索剂量-反应关系,并确定可能从尼亚摄入中获益最多的特定人口群体.
- 为有关预防结石的饮食建议提供基于证据的见解.
主要方法:
- 2007-2018年国家健康和营养检查调查 (NHANES) 数据的横截面分析.
- 利用24小时的饮食回忆来评估素摄入量和石病史的问卷.
- 采用加权后勤回归,限制立方线 (RCS) 和分层分析来进行可靠的统计评估.
主要成果:
- 总共分析了28508名参与者.
- 在完全调整后,较高的食尼亚摄入量与结石患病率 (OR=0.78,95% CI=0.63-0.97) 相反相关.
- 观察到一个L形关系,在60岁以下的成年人中观察到更强的反向关联.
结论:
- 饮食中氨酸摄入量与美国成年人群中结石风险降低有关.
- 这些发现表明,适当的素消费可能在预防结石方面发挥作用,特别是在年轻人中.
- 需要进一步的研究来证实这些发现,并阐明这种关联背后的因果机制.
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