相关实验视频
Updated: May 27, 2025
06:21
Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
10.3K
在化疗期间,急性白血病患者的体能变化
Wenkui Xu1, Zhangjie Li1, Chunfeng Wang1
1The School of Nursing, Fujian Medical University, No. 1 Xueyuan Road, Shangjie Town, Minhou County, Fuzhou City, 350108, Fujian Province, China.
Scientific reports
|February 15, 2025
概括
身体健康,包括BMI和灵活性,在接受化疗的急性白血病患者中显著影响患者报告的结果. 监测和干预,如运动,可以改善患者在治疗期间的幸福感.
科学领域:
- 在瘤学瘤学.
- 运动生理学 运动生理学
- 患者报告的结果
背景情况:
- 急性白血病的治疗包括化疗,这可能会影响患者的身体健康和生活质量.
- 了解身体健康和患者报告结果之间的关系对于优化化疗期间的护理至关重要.
研究的目的:
- 调查新诊断的急性白血病患者在化疗期间身体健康和患者报告结果的变化.
- 检查身体健康参数与患者报告的结果之间的相关性.
主要方法:
- 一项纵向观察性研究,涉及121名新诊断急性白血病的成年患者.
- 在三个时间点评估身体健康:化疗前,化疗期间和初始缓解或两次疗程后.
- 评估了患者报告的结果,并使用了统计分析 (重复测量ANOVA,多重线性回归).
主要成果:
- 关键的身体健康指标,如BMI,平均皮肤厚度,肺容量和灵活性,在化疗期间显著下降,随后出现上升趋势 (T2 < T3 < T1).
- 腰部至部的比率呈现下降,然后增加的模式,而平均握力保持稳定.
- 患者报告的结果得分最初下降,然后增加 (T2 < T1 < T3),BMI,皮厚度,螺旋计和灵活性显著影响了这些结果.
结论:
- 在接受化疗的急性白血病患者中,身体健康是患者报告结果的重要决定因素.
- 医疗保健提供者应积极监测身体健康,并实施运动干预措施,以提高患者在治疗期间的福祉和结果,特别是在骨髓抑制期间.
更多相关视频
07:44Author Spotlight: Implementation of BIVA for Analyzing Disease Risk Factors in Patients with Low Body Cell Mass
Published on: July 14, 2023
1.1K
07:26Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
20.1K
相关概念视频
01:20Exercise and Cardiovascular Response
701
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
701
01:27Disorders of Leukocytes
837
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
837
02:50Combination Therapies and Personalized Medicine
4.8K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.8K
02:53Adaptive Mechanisms in Cancer Cells
5.7K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
5.7K
02:49Cancer Therapies
7.5K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.5K
01:22Bone Marrow Sampling and Transplants
275
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
275