马来西亚的甲辅助治疗患者的认知功能
Izzatul Hani Surohedin1, Tristan Ganes2, Anne Yee3
1Hospital Mesra Bukit Padang, Kota Kinabalu, Malaysia.
Journal of ethnicity in substance abuse
|February 16, 2025
概括
对阿片类药物成的甲辅助治疗 (MAT) 可以导致患者显著的认知障碍,影响诸如记忆和执行功能等领域. 需要进一步的研究,以解决改善干预措施的混因素.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 非医疗性阿片类药物使用是一个重大的公共卫生问题,影响全球数百万人.
- 甲辅助治疗 (MAT) 是阿片类药物成的关键降低危害策略.
- 甲使用可能与认知障碍有关,可能阻碍治疗疗效.
研究的目的:
- 在接受甲辅助治疗 (MAT) 的患者中调查认知功能.
- 为了比较MAT患者和健康对照者的认知表现.
- 确定受MAT影响的特定认知领域.
主要方法:
- 一项涉及114名参与者的横截面研究 (76名MAT患者,38名对照).
- 使用了社会人口统计问卷,DSM-5和神经精神病学认知 (NUCOG) 评估.
- 采用一般线性模型来分析认知功能差异,控制混因素.
主要成果:
- 与对照组相比,MAT患者的总体NUCOG得分明显较低 (p < .001).
- 在视觉构造,记忆,执行和语言领域观察到特定的缺陷 (p < .001).
- 两组之间没有发现注意力得分的显著差异 (p = .457).
结论:
- 在MAT治疗的患者在几个领域表现出显著的认知障碍.
- 在MAT患者的认知缺陷需要进一步调查,以告知治疗策略.
- 解决混因素对于开发有效的阿片类药物成治疗干预措施至关重要.
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