健康饮食指数 (HEI-2020) 评分和结直肠癌风险
Arianna Natale1, Dariush Khaleghi Hashemian1, Jerry Polesel2
1Department of Clinical Sciences and Community Health, Dipartimento di Eccellenza 2023-2027, University of Milan, Milan, Italy.
Cancer epidemiology
|February 16, 2025
概括
坚持美国人饮食指南 (DGA) 与降低结直肠癌 (CRC) 风险有关. 这项研究发现,2020年健康饮食指数 (HEI-2020) 较高的得分与意大利CRC发病率较低有关.
科学领域:
- 营养科学 营养科学
- 癌症流行病学 癌症流行病学
- 公共卫生 公共卫生
背景情况:
- 饮食模式显著影响癌症风险.
- 美国人饮食指南 (DGA) 提供了基于证据的健康饮食建议.
- 评估是否遵守饮食指南可以为预防癌症的公共卫生策略提供信息.
研究的目的:
- 调查2020-2025年美国人饮食指南 (DGA) 的遵守,通过2020年健康饮食指数 (HEI-2020) 测量,与结直肠癌 (CRC) 风险之间的关联.
- 为了评估这个协会在意大利人口.
- 提供关于饮食在CRC预防中的作用的见解.
主要方法:
- 1992年至1996年在意大利进行的一项多中心病例控制研究.
- 包括1953个CRC病例和4154个控制.
- 通过食物频率问卷评估饮食摄入量,使用HEI-2020得分量化DGA对齐.
主要成果:
- 2020年健康饮食指数 (HEI-2020) 的得分从29.4到97.0不等.
- 拥有最高HEI-2020分数的个体表现出显著较低的CRC风险 (OR:0.69,95%CI=0.60-0.80).
- 这种反向关联在结肠癌和直肠癌以及各种人口和生活方式因素中都是一致的.
结论:
- 遵守美国人饮食指南 (DGA) 表明与结直肠癌 (CRC) 风险的反向关联.
- 促进与DGA建议一致的饮食可能是预防CRC在不同人群中的可行策略.
- 这些发现强调了饮食质量在减轻癌症风险方面的重要性.
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