在美国成年人样本中,PTSD症状和酒精使用对工作记忆和执行功能的同时影响
Darrin M Aase1, Stephanie McManimen2, Ryan Holliday3
1Research and Development, VA Pacific Islands Health Care System, 3375 Koapaka St, Suite B220, Honolulu, HI, 96819, USA; The Ohio State University Wexner Medical Center, Department of Psychiatry and Behavioral Health, 1670 Upham Drive, Ste 130, Columbus, OH, 43210, USA.
Journal of psychiatric research
|February 16, 2025
概括
患有创伤后应激障碍 (PTSD) 和酒精使用障碍 (AUD) 的成年人的认知控制是复杂的. 随着酒精使用的增加,决策能力下降,只有在高水平的PTSD症状时才会出现.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 心理学 心理学 心理学
背景情况:
- 创伤后应激障碍 (PTSD) 和酒精使用障碍 (AUD) 经常同时发生.
- 两种PTSD和AUD独立地损害认知功能,包括认知控制.
- 关于PTSD和AUD对认知控制的综合影响的研究有限.
研究的目的:
- 调查PTSD症状严重程度和酒精使用严重程度 (AU) 对工作记忆 (WM) 和执行功能 (EF) 的影响.
- 探索PTSD和AU之间对认知表现的潜在相互作用影响.
- 为制定针对伴随性PTSD和AUD的认知缺陷的干预措施提供信息.
主要方法:
- 112名美国成年参与者完成了PTSD症状严重程度和AU严重程度的评估.
- 参与者还接受了工作记忆 (WM) 和执行功能 (EF) 的测试.
- 统计分析检查了PTSD和AU对认知结果的主要影响和相互作用.
主要成果:
- 没有发现PTSD或AU严重程度对WM或EF的重大主要影响.
- 更高的年龄与WM任务的性能降低有关.
- 一个相互作用效应表明决策能力下降,随着AU的增加,只有在高的PTSD症状水平.
结论:
- 认知控制,特别是决策,受到PTSD和AU严重程度的相互作用的独特影响.
- 年龄是影响工作记忆表现的重要因素.
- 这些发现强调了需要针对性干预来解决伴随性PTSD和AUD的认知缺陷的需要.
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