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Updated: May 27, 2025

Spatiotemporal Subcellular Manipulation of the Microtubule Cytoskeleton in the Living Preimplantation Mouse Embryo using Photostatins
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基于分子对接的基础上发现了一种新型的微管不稳定剂,以向菌素部位

Jiangying Cai1, Miao He1, Yingying Wang1

  • 1The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou 730030, PR China; Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou 730070, PR China.

Biochemical pharmacology
|February 16, 2025
PubMed
概括

一种新的微管不稳定剂 (MDA),C10,通过破坏微管网络并促进亡,有效地抑制瘤生长. 这种胆固醇结合部位抑制剂显示出抗癌潜力,在体内毒性最小.

关键词:
科尔奇辛结合部位抑制剂微管不稳定剂是微管不稳定剂.分子对接是分子对接.虚拟选是一个虚拟的选.

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