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相关概念视频

Autoimmune Disorders01:29

Autoimmune Disorders

379
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
379
Immunological Memory01:23

Immunological Memory

516
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
516
What is the Immune System?01:38

What is the Immune System?

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Overview
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Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

730
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
730
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

209
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
209
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

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Overview
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相关实验视频

Updated: May 27, 2025

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
09:38

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

Published on: September 12, 2016

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在长期COVID中自身免疫.

Shubha Talwar1, James A Harker1, Peter J M Openshaw1

  • 1National Heart and Lung Institute, Imperial College London, London, United Kingdom.

The Journal of allergy and clinical immunology
|February 16, 2025
PubMed
概括

长期COVID或SARS-CoV-2的后急性后续可能涉及自身免疫反应. 研究表明,感染后的B细胞失调和自身抗体可能导致持续的症状.

科学领域:

  • 免疫学 免疫学 免疫学
  • 传染性疾病 传染性疾病
  • 病毒学 病毒学

背景情况:

  • 长期COVID (SARS-CoV-2的急性后续) 影响高达10%的个人在SARS-CoV-2感染后.
  • 由于各种症状,缺乏生物标志物和不清楚的病原体,诊断和治疗具有挑战性.
  • 假设的原因包括病毒持久性,炎症,微生物组变化和自身免疫.

研究的目的:

  • 审查病毒感染后自身免疫反应的机制.
  • 专注于B细胞失调和急性和长期COVID的自身抗体生产的证据.

主要方法:

  • 关于病毒感染和自身免疫反应研究的文献综述.
  • 在SARS-CoV-2感染中分析B细胞异常和自身抗体的证据.
  • 检查自身抗体在长期COVID病变发生过程中的作用.

主要成果:

  • 病毒感染可以通过各种机制触发自身免疫反应.
  • 研究表明,在SARS-CoV-2感染后,自身抗体产生,尽管它们的持久性和作用仍在争论中.
  • B细胞失调与这些自身免疫现象的发展有关.

结论:

关键词:
B细胞失调的调节问题长时间的COVID.这是自抗体的自抗体.这是自身免疫力.

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  • 自身免疫反应,包括B细胞失调和自身抗体产生,是长期COVID的可能因素.
  • 需要进一步的研究来确认自身抗体在长期COVID中的作用和持久性.
  • 了解这些自身免疫机制可能会导致改善长期COVID的诊断和治疗.