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涉及慢性节省神经损伤的VTA多巴胺基神经元疼痛诱导的类似抑郁的行为

Ludi Zhang1, Menghan Ji2, Yufei Sun2

  • 1Department of Pharmacology; The Key Laboratory of Neural and Vascular Biology, Ministry of Education; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Medical University, 050017, Shijiazhuang, Hebei, PR China; College of Forensic Medicine, Collaborative Innovation Center of Forensic Medical Molecular Identification, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University, Shijiazhuang, Hebei 050017, PR China; Identification Center of Forensic Medicine, Hebei Medical University, Shijiazhuang, Hebei 050017, PR China.

Brain research bulletin
|February 16, 2025
PubMed
概括

慢性疼痛和抑郁症通过大脑的多巴胺系统共享联系. 这项研究表明,慢性疼痛增加多巴胺神经元活动,导致抑郁行为,建议新的治疗点.

关键词:
慢性外围神经病痛 慢性外围神经病痛抑郁症 抑郁症 抑郁症多巴胺是一种多巴胺.腹部顶部区域的区域.

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