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Updated: May 27, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

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沙利多米德可以有效地预防IgG4相关疾病的复发超过其副作用:一个多中心,随机,双盲,安慰剂控制的多中心,随机,双盲研究

Yu Chen1, Cong Ye1, Pingting Yang2

  • 1Department of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Annals of the rheumatic diseases
|February 16, 2025
PubMed
概括

与安慰剂相比,thalidomide显著降低了IgG4相关疾病 (IgG4-RD) 患者的复发率. 这项研究表明,thalidomide是预防IgG4-RD复发的安全有效选择,可能允许减少葡萄糖皮质激素的使用.

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