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基于空白频率的夜间多尿症患者的夜间多尿症预测
Teppei Nishiwaki1, Kota Kawase2, Yoshinori Nishino3
1Department of Urology, Graduate School Of Medicine, Gifu University, 1-1, Yanagido, Gifu, Gifu, 501-1194, Japan.
International urology and nephrology
|February 16, 2025
概括
患有夜间多尿症 (NP) 的患者在白天尿尿的频率较低. 夜间到24小时空白频率比率可以帮助预测NP,帮助早期诊断.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年学是一门学科.
背景情况:
- 夜间多尿症 (NP) 显著影响夜间多尿症的管理.
- 了解白天排空模式对于诊断NP至关重要.
- 目前对NP的诊断指标需要进一步改进.
研究的目的:
- 调查夜间多尿症 (NP) 患者的白天排空特征.
- 用空白频率比率来确定NP的新型预测指标.
- 评估夜间到24小时空空频率比率在预测NP中的实用性.
主要方法:
- 在17个日本机构 (2018-2022) 中对875名夜患者进行了回顾性分析.
- 患者分为NP (夜间多尿症指数[NPi]>33%) 和非NP组.
- 分析了空隙频率和体积;进行了相关性和ROC曲线分析.
主要成果:
- 在NP患者中,白天排尿频率显著降低,白天尿量较高 (p < 0.001).
- 夜间到24小时空空频率的比率与NPI正相关 (r=0.38,p <0.001).
- 该比率显示了NP的强大预测能力 (AUC=0.79),截止值为0.23,提供75%的灵敏度和68%的特异性.
结论:
- 患有NP的患者表现出明显的白天排泄模式,包括频率和体积的减少.
- 夜间到24小时的空白频率比率在初始咨询期间作为NP的实际预测指标.
- 进一步的研究和数据积累可以提高这种预测比率的准确性和实用性.
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