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Updated: May 27, 2025

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由tRNA基因组成的障碍物可以补充无处不在的染色体开放元件的好处,以增强转基因表达

Rebecca E Sizer1, Richard M Ingram1, Robert J White1

  • 1Department of Biology, University of York, York, UK.

Biotechnology journal
|February 16, 2025
PubMed
概括

我们发现,与无处不在的染色体开放元素 (UCOEs) 相比,tRNA基因在生物制造中提供了对转基因沉默的优越屏障. 结合两者的混合元素可能会增强长期的基因表达.

关键词:
在CHO细胞中.障碍物元素的障碍物元素生物制造 生物制造 生物制造表观遗传学是指表观遗传学.基因沉默是对基因进行沉默的方法.

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