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Updated: May 27, 2025

Visual Detection of Multiple Nucleic Acids in a Capillary Array
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揭开未来:今天塑造分子诊断的热门话题

Sabine Weiskirchen1, Ralf Weiskirchen1

  • 1Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, Aachen, Germany.

Expert review of molecular diagnostics
|February 17, 2025
PubMed
概括

像下一代测序 (NGS) 和人工智能等先进的诊断技术正在通过改进疾病检测和个性化治疗来彻底改变医疗保健. 解决接入和监管方面的挑战是实现它们对全球健康的全部潜力的关键.

关键词:
人工智能的人工智能是人工智能.芯片上的实验室液体活检活检液体活检微生物组是一个微生物组.纳米技术是纳米技术.这是下一代测序.在医疗保健中心进行检测.远程医疗远程医疗

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DNA Microarrays02:34

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
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Fluorescence in situ hybridization, or FISH, was developed in the early 1980s and has quickly become one of the most widely used techniques in cytogenetics. Labeled probes are used to bind complementary DNA or RNA sequences on a chromosome or in a region within a cell. Earlier, the probes could only be obtained by cloning or reverse transcription of a DNA template. Currently, the probe oligonucleotides can be synthesized synthetically. Additionally, with the advancement of optical techniques,...
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