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抑制KIF11通过影响光受体细胞生和发育中的细胞周期调节来诱导视网膜病变的进展.

Yue Xu1,2, Jie Chen1,2, Xin-Yao Wang1,2

  • 1Department of Cell Biology and Genetics, The School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian, 350122, China.

Advanced biology
|February 17, 2025
PubMed
概括

带有胆红素病变,淋巴或智力发育受损 (MCLMR) 的小头与KIF11基因缺陷有关. 在小鼠中,KIF11的抑制导致视网膜缺陷和视力丧失,揭示了它在乳毛形成和细胞分裂中的作用.

关键词:
在KIF11中,KIF11是KIF11,KIF11是KIF11.中心体 中心体 中心体 中心体摄影受体细胞是一种光受体细胞.主要的纤毛是主要的纤毛.视网膜病变是一种视网膜病变.

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