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Updated: May 27, 2025

Large-scale Top-down Proteomics Using Capillary Zone Electrophoresis Tandem Mass Spectrometry
10:05

Large-scale Top-down Proteomics Using Capillary Zone Electrophoresis Tandem Mass Spectrometry

Published on: October 24, 2018

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在带有电子激活解离的飞行时间仪器上建立一个自上而下的蛋白质组学平台

Richard M Searfoss1, Emily Zahn1, Zongtao Lin1

  • 1Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110, United States.

Journal of proteome research
|February 17, 2025
PubMed
概括

斯凯克斯ZenoTOF 7600系统在自上而下的蛋白质组学方面表现出强的性能,能够准确分析完整的蛋白质及其修改. 这种先进的质谱平台可方便对蛋白序列和翻译后修改进行详细的表征.

关键词:
电子激活解离的解离方式后翻译修改后的修改蛋白质形式的蛋白质形式顶向下的蛋白质组学

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Tandem Mass Spectrometry01:21

Tandem Mass Spectrometry

Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and signal-to-noise ratio for the analyte. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.
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Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
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Proteomics01:33

Proteomics

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