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Updated: May 27, 2025

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library
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作为药理学点的Farnesoid X受体和纤维细胞生长因子15/19

Syeda Maliha1, Grace L Guo1,2,3,4,5

  • 1Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA.

Liver research
|February 17, 2025
PubMed
概括

法内索伊德X受体 (FXR) 激动剂和FGF19类似物显示出治疗非酒精性脂肪肝炎 (NASH) 的前景. 研究还在探索FXR对抗性,为这种肝病进行临床前和临床开发的几种候选药物.

关键词:
胆汁酸 胆汁酸是一种法尔内索伊德X受体 (FXR) 是一种纤维细胞生长因子15 (FGF15)纤维细胞生长因子19 (FGF19)非酒精性脂肪肝炎 (NASH) 是一种非酒精性脂肪肝炎.

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