延迟真菌性假肢关节感染:一个罕见的病例报告
Nikhil Cs1, Sharafuddeen Mammu2, Vishnu Unnikrishnan1
1Department of Orthopaedic Surgery, Baby Memorial Hospital, Kozhikode, Kerala, India.
Journal of orthopaedic case reports
|February 17, 2025
概括
在全膝关节置换术后的真菌感染很罕见,但具有挑战性. 这份病例报告显示,通过分阶段的手术和抗真菌治疗成功管理,导致康复和不复发.
科学领域:
- 整形外科手术 整形外科手术
- 传染病 传染病 传染病
- 菌类学 菌类学是指菌类学.
背景情况:
- 在全膝关节置换 (TKR) 后的真菌假肢关节感染 (PJIs) 不常见,但会带来重大治疗挑战.
- 延迟诊断和对传统疗法的耐药性使真菌PJIs的管理变得复杂.
研究的目的:
- 描述了在接受TKR的患者中延迟的真菌PJI的成功管理.
- 为了突出分阶段手术方法与向抗真菌疗法相结合的有效性.
主要方法:
- 一名65岁的女性患有4岁的TKR呈现了PJI的症状.
- 通过在突液中识别真菌元素来确认诊断.
- 治疗包括分阶段的手术程序与除菌,抗生素抗真菌水泥间隔器,延迟修订和12周的弗卢可纳疗程.
主要成果:
- 患者在干预后经历了症状改善.
- 一年后的随访证实没有感染复发.
- 选择的治疗策略在控制真菌PJI方面被证明是有效的.
结论:
- 阶段性手术干预是一种有效的策略,用于管理TKR后的真菌PJIs.
- 针对性抗真菌疗法,如可纳,对于成功的结果至关重要.
- 长期跟踪对于监测患有真菌PJIs的患者至关重要.
相关概念视频
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Endocarditis III: Medical Management
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Acute Pyelonephritis I: Introduction
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Acute Pyelonephritis II: Diagnostic Studies and Management
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...


