口腔状细胞癌的透明细胞变体:一个罕见的病例
Ananjan Chatterjee1, Swapan K Purkait1, Hiralal Ash2
1Oral and Maxillofacial Pathology, Buddha Institute of Dental Sciences and Hospital, Patna, IND.
Cureus
|February 17, 2025
概括
口腔状细胞癌 (CCSCC) 的透明细胞变体是一种罕见且具有攻击性的口腔病变. 本案例报告详细介绍了其组织病理学特征和诊断标记,强调了其具有挑战性的性质.
科学领域:
- 口腔病理学 口腔病理学
- 在瘤学瘤学.
- 组织病理学 组织病理学
背景情况:
- 口腔状细胞癌 (CCSCC) 的清晰细胞变体是一种不常见且具有攻击性的口腔病变.
- 有限的记录病例凸显了与CCSCC相关的罕见性和诊断挑战.
研究的目的:
- 报告一个口腔状细胞癌 (CCSCC) 清晰细胞变异病例.
- 讨论这种罕见的口腔癌变体的组织病理学发现和诊断工作.
主要方法:
- 口腔病变的组织病理学检查.
- 组织化学和免疫组织化学标记物的应用 (细胞克拉8,18,AE1/AE3,维丁,S100,HMB45).
主要成果:
- 组织病理学揭示了严重失塑的上皮细胞,具有透明的细胞质和角质蛋白珍珠.
- 免疫组织化学证实了对细胞激素的阳性和对维门丁,S100和HMB45的负性,支持了CCSCC诊断.
结论:
- 口腔状细胞癌 (CCSCC) 的透明细胞变异因其稀有性而带来诊断挑战.
- 需要进一步了解CCSCC的生物行为.
相关概念视频
01:30Skin Cancer
3.0K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
3.0K
02:21Cancers Originate from Somatic Mutations in a Single Cell
11.4K
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
11.4K