深度大脑刺激导致自发性肺脑病重吸收后的功能重新定位:临床病例介绍和系统审查
Yeimy Margarita Lebrón Sánchez1, Viviana Torres1, Angel Carreras1
1Parkinson's Disease and Movement Disorders Unit, Neurofunctional Group, Santo Domingo, DOM.
Cureus
|February 17, 2025
概括
帕金森病的深度大脑刺激 (DBS) 后的肺脑炎可以取代电极. 在罕见的情况下,自发的空气再吸收可以重新定位电极,避免手术.
科学领域:
- 神经外科 神经外科
- 神经学 神经学
- 医疗成像医学成像
背景情况:
- 深度大脑刺激 (DBS) 对于晚期帕金森病 (PD) 在药物失效时至关重要.
- 由于肺脑病导致的电极位移是DBS手术后的潜在并发症.
研究的目的:
- 在帕金森病中报告一例肺脑病引起的电极位移自发解决的病例.
- 系统地审查DBS后与肺脑病相关的电极位移的发生率和管理.
主要方法:
- 一个61岁的男性患有PD,接受STN-DBS的病例报告.
- 对24项关于肺脑病和DBS电极位移的研究 (1,439名患者) 的系统综述.
- 对成像,空气体积和临床结果的分析.
主要成果:
- 病例患者经历了自发的电极重新定位后肺脑重吸收.
- 系统性审查发现,在75%的病例中,电极发生了位移.
- 自发的重新定位发生在12.5%的病例中,主要是空气体积小 (<10厘米3).
结论:
- 自发性肺脑病重吸收可以解决电极位移,但这是罕见的.
- 由于肺脑炎引起的电极位移的管理策略缺乏标准化.
- 需要进一步的研究,以建立基于证据的指导方针来管理这种并发症,以优化DBS的结果.
相关概念视频
Pneumonia I: Introduction
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Acute Respiratory Failure-III
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without causing...
Acute Respiratory Failure-IV
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Atelectasis II: Pathophysiology
Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
Pneumonia I: Introduction
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...


