非酒精性脂肪肝疾病:饮食和营养药的方法
Ludovica Cogorno1, Elena Formisano2,3, Andrea Vignati2
1Department of Experimental Medicine-Medical Pathophysiology, Food Science and Endocrinology Section, Sapienza University of Rome, Rome, Italy.
饮食干预和营养保健品在治疗非酒精性脂肪性肝病 (NAFLD) 中表现有前途. 本综述考察了地中海饮食和间歇性禁食等饮食,以及补充剂,以减缓NAFLD的进展.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 是全球普遍存在的慢性肝病.
- 代谢综合征和遗传因素增加了NAFLD进展到NASH,纤维化和肝衰竭的风险.
研究的目的:
- 审查各种饮食和营养药对NAFLD发展和进展的影响.
- 确定减轻NAFLD相关肝病的饮食和补充策略.
主要方法:
- 关于饮食方法的文献综述,包括地中海,高蛋白,低碳水化合物/高脂肪,高碳水化合物/低脂肪饮食和间歇性禁食.
- 对证明有效改善NAFLD的营养药物进行分类和审查.
主要成果:
- 特定的饮食和营养保健品在管理NAFLD方面显示出潜力.
- 营养药物被分为植物性,维生素类,脂肪酸和微生物群管理工具.
结论:
- 饮食修改和有针对性的营养药物干预是延缓NAFLD进展的有希望的策略.
- 对这些干预措施的进一步研究可以为NAFLD管理的临床实践提供信息.
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