在恶性胃出口阻塞中,在EUS引导的胃肠静脉切除术后,早期死亡的预测因素
Hyuk Lee1, Kenneth Hyunsoo Park2, Ulysses Rosas2
1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
针对恶性胃出口阻塞 (mGOO) 的内超声导向胃肠静脉切除术 (EUS-GE) 显示出高成功率,但具有早期死亡风险. ,特别是2级或更高的,独立地预测了手术后的早期死亡.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
- 在瘤学瘤学.
背景情况:
- 透视超声导向胃肠静脉切除术 (EUS-GE) 是一种针对恶性胃出口阻塞 (mGOO) 的新型治疗方法.
- EUS-GE提供了长时间的通透性和低的再干预率.
- 由于程序的风险和成本,仔细选择患者至关重要.
研究的目的:
- 为了确定mGOO患者在EUS-GE后早期死亡的预测因素.
- 改进EUS-GE程序的患者选择标准.
主要方法:
- 对接受EUS-GE.GE.治疗的无法切除的mGOO患者的回顾性分析.
- 单变量和多变量处罚概率30天死亡预测因子的Firth逻辑回归.
- 评估原油和调整后的危险比率.
主要成果:
- 高技术 (96.7%) 和临床 (93.1%) 的成功率为EUS-GE.
- 整体30天死亡率为11.7%,没有与手术相关的并发症.
- 基线ECOG表现状况差 (≥2) 和结与更高的30天死亡率有关.
- 2级炎独立预测了30天的死亡率 (aHR 52.41,P=0.024).
结论:
- EUS-GE对mGOO有效,但需要对患者进行仔细的选择.
- 酸,特别是2级或更高的酸,是EUS-GE后早期死亡的重要独立预测因素.
- 在接受EUS-GE的mGOO患者中,考虑形状对于风险分层至关重要.
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