用PSI评估老年ERCP患者的镇静深度:一个前性队列研究
Lei Huang1,2, Lin-Lin Liu1,2, Yong-da Lu3
1Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People's Republic of China.
Clinical interventions in aging
|February 17, 2025
概括
患者状态指数 (PSI) 在ERCP期间有效监测老年患者的镇静深度. 一个PSI50 (48-52) 表示足够的镇静,与MOAA/S得分相对应.
科学领域:
- 麻醉学 麻醉学
- 胃肠病学 胃肠病学
- 老年病的医生 老年病的医生
背景情况:
- 适度镇静对于接受内镜逆流胆细胞造影 (ERCP) 的老年患者至关重要.
- 患者状态指数 (PSI) 是一种实时麻醉深度监测工具.
- 修改观察者评估警觉/镇静 (MOAA/S) 尺度通常用于评估镇静水平.
研究的目的:
- 在接受ERCP的老年患者中评估PSI和MOAA/S得分之间的相关性.
- 为了确定一个目标PSI范围,在ERCP期间在这个人群中进行足够的镇静.
主要方法:
- 对57名接受ERCP的老年患者进行前性队列研究.
- 普罗波注入量进行了定位,以达到1或2的MOAA/S得分.
- 在程序和恢复过程中记录了PSI和MOAA/S得分.
- 监测过量,不良事件和疲劳.
主要成果:
- 在PSI和MOAA/S得分之间发现了显著的正相关性 (ρ = 0.742,P < 0.001).
- 当患者的MOAA/S分数为1和2时,PSI中位数为50 (95%CI:48-52).
- 在8.8%的患者中发生过度食 (PSI <25),EEG爆发抑制在5.3%的患者中发生.
- 没有报告过脱或过程内意识;不良事件不常见.
结论:
- 在老年ERCP患者的实时镇静监测中,PSI是一个有价值的工具.
- 一个PSI范围为48-52似乎对应于足够的镇静水平 (MOAA/S 1-2).
- 这种监测可以帮助优化镇静,并有可能减少ERCP期间的过度镇静.
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