-

Ying Dai1, Yan Wang1, Youfei Fan1

  • 1Department of Pediatrics, Shandong Province Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

Frontiers in pediatrics
|February 17, 2025
PubMed
概括

儿科扩展性心肌病 (DCM) 具有显著的遗传多样性,已确定超过100个基因. 了解这些遗传变异是改善患有这种严重心脏病的儿童诊断和治疗的关键.

相关概念视频

Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.4K
Pedigree Analysis01:35

Pedigree Analysis

Overview
83.7K
Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
20.9K
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
522