印度尼西亚的新兴疟疾:Plasmodium knowlesi感染的概述
Nisa Fauziah1,2,3,4, Karomahul Malaya Jati5, Fedri Ruluwedrata Rinawan6,7,8
1Division of Parasitology, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Jl. Prof. Eyckman No. 38, Sukajadi, Bandung 40161, West Java, Indonesia.
Parasite epidemiology and control
|February 17, 2025
概括
在印度尼西亚,Plasmodium knowlesi疟疾正在出现,超过31%的分析病例是在加里曼坦和苏门答腊发现的. 男性和来自加利曼坦的个人面临更高的风险,突出了针对性控制策略的需要.
科学领域:
- 医学昆虫学 医学昆虫学
- 传染性疾病 传染性疾病
- 寄生虫学的寄生虫学
背景情况:
- 疟原虫 (Plasmodium knowlesi) 是东南亚疟疾的新兴原因,对印度尼西亚等地区产生重大影响.
- 这种猿类疟疾寄生虫正在成为一种主导物种,改变了流行病学格局.
研究的目的:
- 提供印尼Plasmodium knowlesi疟疾病例的概述.
- 分析研究区域中与P. knowlesi感染相关的风险因素.
主要方法:
- 来自印度尼西亚国家转诊疟疾实验室 (2011-2020) 的二次数据分析.
- 对212个样本进行检查,以确定P. knowlesi感染以及相关的人口和地理因素.
主要成果:
- 在212个样本中,66个 (31.1%) 对P. knowlesi呈阳性,其中包括一个混合感染.
- 男性 (OR=2.23) 和来自加利曼丹的个人 (OR=3.97) 的风险明显更高.
- 在P. knowlesi风险和年龄组或职业 (室内与室外工作) 之间没有发现显著的关联.
结论:
- 苏门答腊和加利曼坦岛屿对P. knowlesi疟疾有很大的风险.
- 风险因素包括性别和地理来源,强调了超越自然宿主和载体的复杂性.
- 针对P. knowlesi的常规PCR对于对抗这种猿类疟疾寄生虫的有效控制策略至关重要.
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