在一般人群中抗真菌过敏的流行率
Meron W Shiferaw1, Monica A Donnelley1, George R Thompson2,3
1Department of Pharmacy, University of California-Davis Medical Center, Sacramento, CA, USA.
The Journal of antimicrobial chemotherapy
|February 17, 2025
概括
抗真菌过敏很常见,而可纳是最常见的罪祸首. 这些过敏率与抗菌药物所见的过敏率相似,突出显示出严重的临床担忧.
科学领域:
- 临床医学 临床医学
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 侵入性真菌感染正在增加,导致抗真菌治疗的使用增加.
- 对抗真菌药物的过敏反应使患者管理复杂化.
- 关于报告的抗真菌过敏的发生率的数据有限.
研究的目的:
- 确定在一个大型学术卫生系统内报告的抗真菌过敏的患病率.
- 确定在接受抗真菌剂的患者中抗真菌过敏的发生率.
- 为了确定与抗真菌过敏相关的因素.
主要方法:
- 在2023年,五个学术中心的170多万名患者遭遇的回顾性队列审查.
- 分析已记录的抗真菌过敏和抗真菌剂的使用情况.
- 计算各种抗真菌剂的流行率和发病率.
主要成果:
- 共有2602名患者报告抗真菌过敏.
- 抗真菌过敏的患病率对可纳 (0.093%) 是最高的.
- 在接受治疗的患者中,抗真菌过敏的发生率为2.98%.
结论:
- 抗真菌过敏的患病率随着年龄和抗真菌治疗的使用而增加.
- 报告的抗真菌过敏率与抗菌剂过敏率相当.
- 可纳显示出报告过敏的最高率.
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