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Updated: May 27, 2025

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
10:21

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在IRF2-INPP4B路径加剧了急性髓性白血病

Xiangqin Xing1, Mei Zhang1, Shengfen Tan1

  • 1Bengbu Medical University, Department of Hematology, Bengbu, P.R. China

Turkish journal of haematology : official journal of Turkish Society of Haematology
|February 17, 2025
PubMed
概括

干扰素调节因子2 (IRF2) 和伊诺西聚酸4-酸酶B (INPP4B) 在T细胞中发出信号,促进急性髓性白血病 (AML) 细胞的存活. 这一途径激活了JAK2-STAT3信号,减少了细胞亡并加剧了AML的进展.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.细胞灭亡 (apoptosis) 是一种死亡的过程.在 IRF2-INPP4B 中,您可以选择 IRF2-INPP4B.JAK2-STAT3信号通道是一个信号通道.

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