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Updated: May 27, 2025

Maintaining Human Glioblastoma Cellular Diversity Ex vivo using Three-Dimensional Organoid Culture
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NUP98-p65复合体调节DNA修复,以维持质母细胞瘤干细胞

Feifei Li1, Ying Zhang1, Jiahui Li1

  • 1Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, China.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|February 17, 2025
PubMed
概括

核素98 (NUP98) 通过调节DNA修复途径,促进质母细胞干细胞的生存和对治疗的抵抗. 针对NUP98可能为治疗多形质母细胞瘤 (GBM) 提供新的策略.

关键词:
在DNA损伤和修复过程中.在 NUP98 里面,你会看到 NUP98.质母细胞瘤是一种质母细胞瘤.质母细胞的干细胞核孔复合体是核孔复合体.

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