患有广泛回避性限制性食物摄入障碍表型儿童的精神和体质状况
Marie-Louis Wronski1,2,3,4, Ralf Kuja-Halkola1, Elin Hedlund1
1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
JAMA pediatrics
|February 17, 2025
概括
患有回避性限制性食物摄入障碍 (ARFID) 的儿童患神经发育,胃肠道和呼吸系统疾病的风险明显更高. 这项研究突出了ARFID年轻人的复杂健康需求,强调了全面儿科护理的重要性.
科学领域:
- 儿科健康 儿科健康
- 饮食障碍 饮食障碍 饮食障碍 饮食障碍
- 临床流行病学临床流行病学
背景情况:
- 避免性限制性食物摄入障碍 (ARFID) 影响儿童的身体健康和心理社会功能.
- 患有ARFID的儿童经常表现出各种精神和体征症状,导致跨儿科子专业的咨询.
- 在ARFID中,关于并存疾病的大规模数据有限.
研究的目的:
- 描述青少年被诊断患有ARFID的综合医疗保健需求.
- 确定ARFID儿童共存的精神和体质疾病的范围和患病率.
主要方法:
- 一项使用瑞典儿童和青少年双胞胎研究 (CATSS) 和瑞典国家患者登记册的队列研究.
- 使用来自家长报告和注册数据的复合措施,识别具有广泛ARFID表型 (6-12岁) 的儿童.
- 分析了1000多个ICD代码,以评估90种不同的精神和体质结果,包括住院治疗日.
主要成果:
- 在30795名参与者中,有616名儿童 (2.0%) 符合ARFID广泛的表型标准.
- 患有ARFID的儿童显著增加神经发育 (如自闭症,智力障碍),胃肠道 (如GERD),呼吸道和神经系统疾病的风险.
- 与对照组相比,ARFID与更明显的精神诊断和更长的住院时间有关,精神疾病的发病时间较早.
结论:
- 这项研究提供了广泛的证据,证明了ARFID大型队列中的共存条件.
- 患有ARFID的年轻人呈现出复杂的健康状况,需要在所有儿科专业领域给予关注.
- 这些发现强调了对ARFID儿童综合护理方法的迫切需要.
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