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使用大型语言模型进行手动与人工智能辅助预选-随机临床试验

Ozan Unlu1,2,3, Matthew Varugheese1,4,5, Jiyeon Shin1,4,5

  • 1Accelerator for Clinical Transformation, Cardiovascular Division, Mass General Brigham, Somerville, Massachusetts.

JAMA
|February 17, 2025
PubMed
概括

No abstract available in PubMed .

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Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
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Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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