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Updated: May 27, 2025

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双特异性酸酶DUSP21是一种STAT3的新型负反调节剂

Shota Shikata1, Kazuna Kikkawa1, Masahiro Fujimuro1

  • 1Department of Cell Biology, Kyoto Pharmaceutical University, Kyoto, 607-8412, Japan.

Biochemical and biophysical research communications
|February 17, 2025
PubMed
概括

白血病抑制因子 (LIF) 诱导DUSP21,一种非典型的双特异性酸酶 (aDUSP),它抑制了LIF/STAT3信号通路. DUSP21直接去化STAT3,抑制其转录活动.

关键词:
细胞因子信号传递在 DUSP2121 中,酸酶是一种酸酶.在STAT3中,我们可以使用STAT3.

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