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Updated: May 27, 2025

Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma
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BIX01294通过抑制谷氨酸酶介导的谷氨动力学来抑制PDAC生长

Se Seul Im1, Jihyeon Seo1, Ji Eun You1

  • 1Department of Biochemistry and Molecular Biology, Brain Korea 21 project, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, South Korea.

Molecular metabolism
|February 17, 2025
PubMed
概括

BIX01294 (BIX) 通过向谷氨酸酶 (GLS) 来抑制胰腺癌细胞的生长. 这种表观遗传调节影响细胞氧化还原平衡,为胰腺管道腺癌 (PDAC) 提供了潜在的治疗策略.

关键词:
BIX0129494 这是一个很好的例子.谷氨酸胺酶的使用方法葡萄糖氨酸 (Glutathione) 是一种这就是KDM6B.胰腺癌是一种胰腺癌.

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