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基于运动的干预措施在预防乳腺癌患者与癌症治疗相关的心脏功能障碍的有效性:系统性审查和网络元分析
Dandan Zhang1, Xingyu Xiong2, Hexiao Ding3
1Sun Yat-sen University, School of Nursing, Guangzhou, Guangdong, China.
International journal of nursing studies
|February 17, 2025
概括
运动干预措施在接受治疗的乳腺癌患者中显示出改善心脏功能的潜力. 然而,这些益处的确定性,特别是来自有氧和抵抗运动的联合益处,非常低,需要进一步研究.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 运动科学 运动科学
背景情况:
- 乳腺癌患者在治疗后面临心脏功能障碍的高风险.
- 运动可以改善心肺呼吸能力,但其在预防心脏功能障碍方面的作用尚不清楚.
研究的目的:
- 评估运动干预措施,以预防与癌症治疗有关的心脏功能障碍.
- 确定癌症患者心脏保护的最佳运动方式.
主要方法:
- 对13项随机对照试验 (1122名参与者) 的系统综述和网络元分析.
- 搜索了主要的数据库 (PubMed,Embase等) 在2024年8月之前.
- 在R软件中使用元分析分析分析心脏功能参数.
主要成果:
- 与常规护理相比,运动干预显著改善了左心室喷射率和全球纵向应变.
- 综合有氧和抵抗运动在改善左心室喷射率方面排名最高 (SUCRA 0.96).
- 综合有氧运动和阻力运动也在全球纵向应变方面排名最高 (SUCRA 0.88).
结论:
- 关于运动干预措施在预防癌症治疗相关心脏功能障碍方面的潜在有效性,存在非常低的确定性.
- 需要进一步的严格研究来证实基于运动的干预措施在这个患者群体中的有效性.
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