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Updated: May 27, 2025

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
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CHAMP1复合体指导异染色蛋白组合,并促进同质性指导的DNA修复

Feng Li1, Tianpeng Zhang2, Aleem Syed3

  • 1Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. feng_li@dfci.harvard.edu.

Nature communications
|February 17, 2025
PubMed
概括

在这些区域中,CHAMP1复合体有助于构建异染色质和修复DNA双链断裂 (DSB). 这个复合体中的缺陷与CHAMP1综合征有关,影响DNA修复.

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