青少年系统性红斑狼的眼部表现:一个系统性审查
Anna Nikolaidou1, Theodora Gianni2, Athanasia Sandali2
1Institute for Ophthalmic Research, University of Tuebingen, Tuebingen, Germany. anniko744@gmail.com.
Eye (London, England)
|February 17, 2025
概括
幼年发作的全身性红斑狼 (JSLE) 可以导致儿童罕见但严重的眼睛问题. 本综述强调了视网膜疾病和干眼等常见的眼部问题,强调了早期检测和管理的必要性.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 眼科医生 眼科 眼科
- 自免疫性疾病 自免疫性疾病
背景情况:
- 幼儿发作系统性红斑狼 (JSLE) 是一种慢性自身免疫性疾病,影响儿童和青少年.
- 在JSLE的眼部表现很少见,但可以显著影响患者的预后和生活质量.
- 对JSLE对儿科眼部健康的具体影响需要进一步研究.
研究的目的:
- 系统地审查和巩固目前关于JSLE儿科患者眼部表现的证据.
- 在儿童和青少年中分类和描述与JSLE相关的眼睛疾病范围.
主要方法:
- 在MEDLINE和ScienceDirect上进行了系统的文献搜索,直到2024年10月.
- 包括专注于患有眼部症状的儿科JSLE患者的研究.
- 质量评估使用了乔安娜·布里格斯研究所的批判性评估工具;分析了42项研究.
主要成果:
- 视网膜干扰是最常见的眼部表现.
- 常见的问题包括干眼病,脑膜炎,血管闭合性视网膜病变和皮质类固醇诱导的白内障.
- 眼部症状有时表现为JSLE发病的最初迹象.
结论:
- 在JSLE的眼部表现,特别是视网膜疾病,需要提高临床意识.
- 标准化眼科评估对于有效管理与JSLE相关的眼睛疾病至关重要.
- 进一步的研究是必不可少的,以了解JSLE.眼部参与的病变发生.
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