投资组合饮食得分与乳腺癌风险的关联:从病例控制分析的见解
Sazin Yarmand1, Negin Atashi2, Iman Kazemi3
1Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
BMC cancer
|February 18, 2025
概括
基于植物的组合饮食 (PD) 可能会降低乳腺癌 (BC) 风险. 较高的PD分数 (PDS) 与更低的BC几率有关于绝经前妇女,植物蛋白摄入量在所有妇女中都显示出保护作用.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 投资组合饮食 (PD) 是一种基于植物的饮食模式,与减少癌症死亡率有关.
- 调查组合饮食得分 (PDS) 和乳腺癌 (BC) 风险对于了解饮食对预防癌症的影响至关重要.
- 这项研究侧重于伊朗妇女在不同更年期的不同阶段.
研究的目的:
- 为了检查投资组合饮食得分 (PDS) 与伊朗妇女乳腺癌 (BC) 风险之间的关联.
- 探索饮食模式如何影响与更年期状态相关的BC风险.
- 在PD中识别特定的饮食成分,这些成分可以提供对BC的保护.
主要方法:
- 一项病例控制研究涉及133名新诊断BC的妇女和265名对照.
- 通过验证的半定量食品频率问卷 (168种食品) 评估了饮食摄入量.
- 使用后勤回归分析计算PDS和BC关联的几率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 植物蛋白摄入量增加与总人口中较低的BC几率显著相关 (OR=0.399).
- 较高的PDS显示出与降低BC几率的显著关联在绝经前妇女 (OR=0.914).
- 在绝经后的女性中,增加植物蛋白摄入量与显著降低BC几率 (OR=0.078) 有关.
结论:
- 较高的PDS与乳腺癌的几率降低有关,特别是在绝经前妇女中.
- 植物蛋白摄入量在一般人群和绝经后妇女中都显示出对乳腺癌的保护作用.
- 组合饮食可以作为一种有益的预防性饮食策略来预防乳腺癌,其中植物蛋白质是关键组成部分.
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