实现机器学习在精密瘤学中的承诺:专家对机遇和挑战的观点
Vasileios Nittas1,2, Kelly E Ormond2, Effy Vayena2
1Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, Zurich, 8001, Switzerland.
BMC cancer
|February 18, 2025
概括
精确瘤学的机器学习 (ML) 是新生的,但对个性化癌症护理有希望. 克服数据访问,临床实用性和道德挑战对于其未来的整合至关重要.
科学领域:
- 精确瘤学是一门精确的专业.
- 医疗人工智能的人工智能
- 生物信息学是一种生物信息学.
背景情况:
- 机器学习 (ML) 在分析精确瘤学的复杂患者数据方面显示出潜力.
- 在数字病理学和放射学中,ML应用正在进步,在基因组和表观遗传数据分析中新兴使用.
研究的目的:
- 捕捉专家对ML在精密瘤学当前状态,挑战和未来的观点.
- 确定将ML纳入癌症治疗的机会和伦理考虑.
主要方法:
- 与学术和临床专家进行半结构面试.
- 定性数据分析以确定与精密瘤学中的ML相关的主题.
主要成果:
- 精密瘤学的ML处于早期阶段,临床整合有限.
- 专家强调了ML在改善工作流程和治疗决策方面的潜力,但指出了数据访问,临床实用性和指导方针方面的障碍.
- 关键的伦理问题包括隐私,公平,可解释性和信任.
结论:
- 机器学习为推进癌症研究和以患者为中心的护理提供了巨大的潜力.
- 解决数据访问,临床验证,监管框架和伦理问题对于实现ML在精密瘤学的未来至关重要.
关键词:
算法偏差是一种算法偏差.人工智能的人工智能是人工智能.这是一个偏见的偏见.黑盒子是一个黑盒子.伦理学 伦理学 伦理学可以解释的可解释性.机器学习是机器学习.透明度 (Opacity) 是指一个透明度.精确瘤学是一门精确的专业.隐私 隐私 隐私 隐私 隐私 隐私更多相关视频
04:09Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma
Published on: October 10, 2018
8.2K
07:15Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
Published on: August 16, 2020
6.6K
相关概念视频
02:50Combination Therapies and Personalized Medicine
4.8K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.8K
02:43Mouse Models of Cancer Study
5.5K
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
5.5K